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A 25-year-old male with severe depression who does not want to take medication.
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A 35-year-old woman with both depression and obsessive-compulsive disorder.
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A 45-year-old male with mild to moderate major depression and significant psychosocial stress.
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A 55-year-old woman who has failed adequate trials of 2 different SSRIs and has a 20-year history of recurrent depression.
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Cognitive behavioral therapy alone would never be appropriate.
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